| Red Salamander | 90 | | No | Pierce | 25% Nature 25% Body |
| Sand Wurm | 105 | Vermin | No | Pierce | 15% Nature 15% Soul 15% Mind 15% Body |
| Savanna Lion | 125 | | No | Pierce | 20% Blunt 20% Soul -4% Mind |
| Scorpion | 5 | | No | Pierce | -10% Blunt 25% Nature 25% Soul 25% Body 100% Poison |
| Sewer Rat | 23 | | No | Pierce | -4% Blunt 10% Cut |
| Snake | 2 | Vermin | No | Pierce | 75% Poison |
| Sonic Flyer | 6 | Vermin | No | Pierce | 25% Nature 25% Poison |
| Spectral Dragon of Roachard | 94 | | Yes | Pierce | 100% Blunt 100% Pierce 100% Cut 50% Arrow 50% Poison 50% Disease |
| Spider | 3 | Vermin | No | Pierce | |
| Squalid Ghost | 23 | | No | Pierce | 20% Nature 20% Soul 20% Mind -20% Body 75% Poison 75% Disease |
| Swamp Beast | 105 | | No | Pierce | 100% Poison 100% Disease |
| Talazarian Berserker | 104 | Humanoid | No | Pierce | 50% Blunt 50% Poison 50% Disease |
| Termigon Worker | 24 | | No | Pierce | |
| Thief | 16 | Humanoid | No | Pierce | |
| Thought Destroyer | 118 | | No | Pierce | 25% Soul 100% Mind 100% Poison |
| Tiger | 91 | | No | Pierce | 10% Blunt -4% Cut |
| Titan Scorpion | 85 | Insect | No | Pierce | 50% Cut 15% Nature 100% Poison |
| Triddle | 1 | | No | Pierce | 25% Pierce 25% Cut |
| Web Spinner Spider | 50 | | No | Pierce | -5% Pierce 100% Poison |
| Wyvern Nestling | 75 | Wyvern | No | Pierce | 20% Arrow 20% Nature 100% Poison |