| Deadwillow Root | 24 | | No | | |
| Death Tyrant | 72 | | No | | 15% Soul 15% Body |
| Deep Shadow | 27 | | No | | |
| Deer | 3 | | No | | |
| Demon | 110 | Demon | No | Cut | |
| Desert Giant | 85 | Giant | No | Cut | 25% Blunt 25% Pierce 50% Arrow 75% Nature 50% Mind |
| Desert Giant Noble | 140 | Giant | No | Blunt | 50% Blunt 50% Pierce 50% Arrow 80% Nature 50% Mind |
| Desert Whiptail | 42 | | No | | |
| Deathcap | 135 | | Yes | | 25% Blunt 25% Pierce 25% Cut 20% Arrow 25% Nature 25% Body 100% Poison 100% Disease |
| Der Schlaechter | 150 | | Yes | | 30% Blunt 100% Soul 100% Mind 30% Disease |
| Dunkelklinge | 125 | Demon | Yes | Blunt | 50% Pierce 30% Cut 50% Poison 50% Disease |
| Dwarf Mine Master | 175 | | Yes | Cut | 50% Blunt 50% Arrow 50% Nature 50% Body |
| Darkwing the Mindless | 225 | | Yes | Pierce | 25% Cut -4% Soul 100% Mind 100% Poison |
| Dark Dragon of Roachard | 44 | Dragon | Yes | Cut | 50% Arrow 50% Nature 75% Soul 75% Mind 50% Body 100% Poison 100% Disease |