| Name | Level | Type | Boss | Damage Type | Resistances |
|---|---|---|---|---|---|
| Son of Scalo | 145 | Yes | Cut | 20% Pierce 20% Nature 25% Body 100% Poison | |
| Sonic Flyer | 6 | Vermin | No | Pierce | 25% Nature 25% Poison |
| Spectral Demon Overlord | 90 | No | |||
| Spectral Destroyer | 78 | No | |||
| Spectral Dragon of Roachard | 94 | Yes | Pierce | 100% Blunt 100% Pierce 100% Cut 50% Arrow 50% Poison 50% Disease | |
| Spectral General | 73 | No | 25% Cut 25% Body 25% Poison 25% Disease | ||
| Spectral Horned Berserker | 58 | No | |||
| Spectral Orc Footman | 35 | No | |||
| Spectral Orc Forager | 29 | No | |||
| Spectral Orc Foreman | 44 | No | |||
| Spectral Orc Warrior | 49 | No | |||
| Spectral Orc Wizard | 59 | No | |||
| Spectral Pet | 50 | No | 25% Nature 25% Soul 25% Mind 25% Body | ||
| Spectre of Ryonkah | 115 | No | 20% Arrow 66% Soul 100% Poison | ||
| Spider | 3 | Vermin | No | Pierce | |
| Spider Queen | 15 | No | 100% Poison | ||
| Squalid Ghost | 23 | No | Pierce | 20% Nature 20% Soul 20% Mind -20% Body 75% Poison 75% Disease | |
| Squid | 60 | No | |||
| Stag | 20 | No | |||
| Stone Giant | 80 | No | Blunt |