| Darkwing the Mindless | 225 | | Yes | Pierce | 25% Cut -4% Soul 100% Mind 100% Poison |
| Dwarf Mine Master | 175 | | Yes | Cut | 50% Blunt 50% Arrow 50% Nature 50% Body |
| Der Schlaechter | 150 | | Yes | | 30% Blunt 100% Soul 100% Mind 30% Disease |
| Desert Giant Noble | 140 | Giant | No | Blunt | 50% Blunt 50% Pierce 50% Arrow 80% Nature 50% Mind |
| Deathcap | 135 | | Yes | | 25% Blunt 25% Pierce 25% Cut 20% Arrow 25% Nature 25% Body 100% Poison 100% Disease |
| Dunkelklinge | 125 | Demon | Yes | Blunt | 50% Pierce 30% Cut 50% Poison 50% Disease |
| Dwarven Guardian | 120 | | No | Cut | 25% Arrow 25% Soul 10% Mind -4% Poison |
| Dwarven Miner | 112 | | No | Cut | 20% Cut 20% Arrow 10% Nature 15% Body |
| Demon | 110 | Demon | No | Cut | |
| Dwarf Prospector | 103 | | No | Cut | 25% Pierce -4% Cut 25% Mind |
| Darok the Banished | 100 | | No | | |
| Dragon Egg Minder | 100 | Insect | No | Pierce | -10% Blunt 20% Arrow 50% Nature 100% Poison |
| Desert Giant | 85 | Giant | No | Cut | 25% Blunt 25% Pierce 50% Arrow 75% Nature 50% Mind |
| Dune Crawler | 75 | | No | | 25% Nature 100% Poison |
| Dolphin | 74 | | No | | |
| Death Tyrant | 72 | | No | | 15% Soul 15% Body |
| Diseased Ghoul | 72 | | No | | 5% Cut -10% Soul 100% Disease |
| Dwarven Pirate | 58 | | No | | 20% Pierce |
| Dire Wolf Pack Leader | 54 | | No | | -3% Pierce 5% Magic Missile |
| Dire Wolf | 50 | | No | | |