| Shade | 20 | | No | | 25% Pierce 25% Soul 25% Body 50% Disease |
| Shadow | 17 | | No | Cut | 50% Blunt 25% Pierce 25% Cut 25% Arrow 25% Nature 25% Soul 25% Mind 25% Body 25% Poison 25% Disease |
| Shadow Spider | 62 | | No | | 100% Poison |
| Shambler | 22 | Humanoid | No | | |
| Slimy Ooze | 4 | | No | Body | -10% Blunt 3% Body |
| Sheep | 2 | | No | Blunt | 50% Disease |
| Sickly Troll | 65 | Giant | No | | |
| Silverback | 109 | | No | Blunt | 25% Blunt 10% Pierce |
| Skeletal Apprentice | 8 | | No | | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Skeletal Fiend | 78 | | No | | -5% Soul |
| Skeletal Mage | 12 | | No | Blunt | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Skeletal Pet | 9 | | No | Blunt | -10% Blunt |
| Skeletal Pup | 6 | | No | | -25% Blunt 5% Pierce 5% Cut 25% Arrow 5% Soul 100% Poison 100% Disease |
| Skeleton | 10 | | No | Blunt | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Skeleton Pirate | 48 | | No | Cut | -4% Blunt 20% Pierce 20% Mind -10% Body |
| Skeleton Warrior | 17 | | No | Cut | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Skeleton Wolf | 32 | | No | | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Spectral Dragon of Roachard | 94 | | Yes | Pierce | 100% Blunt 100% Pierce 100% Cut 50% Arrow 50% Poison 50% Disease |
| So Kang Kang | 200 | Animal | Yes | Blunt | 50% Blunt -5% Cut 75% Mind 50% Body |
| Sandy Claws | 135 | | Yes | Cut | 20% Blunt 25% Pierce 50% Cut 20% Soul 20% Mind |