| Small Crab | 28 | Sea Creature | No | Cut | 20% Pierce 50% Arrow -20% Soul 10% Mind |
| Swamp Slug | 27 | | No | | -10% Pierce 25% Disease |
| Sewer Rat | 23 | | No | Pierce | -4% Blunt 10% Cut |
| Squalid Ghost | 23 | | No | Pierce | 20% Nature 20% Soul 20% Mind -20% Body 75% Poison 75% Disease |
| Shambler | 22 | Humanoid | No | | |
| Shade | 20 | | No | | 25% Pierce 25% Soul 25% Body 50% Disease |
| Schlag the Scorpiones | 20 | | Yes | | 100% Poison |
| Stag | 20 | | No | | |
| Shadow | 17 | | No | Cut | 50% Blunt 25% Pierce 25% Cut 25% Arrow 25% Nature 25% Soul 25% Mind 25% Body 25% Poison 25% Disease |
| Skeleton Warrior | 17 | | No | Cut | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Spider Queen | 15 | | No | | 100% Poison |
| Skeletal Mage | 12 | | No | Blunt | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Skeleton | 10 | | No | Blunt | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Skeletal Pet | 9 | | No | Blunt | -10% Blunt |
| Small Grizzly Bear | 8 | | No | Cut | |
| Skeletal Apprentice | 8 | | No | | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Sonic Flyer | 6 | Vermin | No | Pierce | 25% Nature 25% Poison |
| Skeletal Pup | 6 | | No | | -25% Blunt 5% Pierce 5% Cut 25% Arrow 5% Soul 100% Poison 100% Disease |
| Scorpion | 5 | | No | Pierce | -10% Blunt 25% Nature 25% Soul 25% Body 100% Poison |
| Small Skeleton | 5 | | No | Blunt | -25% Blunt 5% Pierce 5% Cut 25% Arrow |