| Sea Turtle | 52 | | No | | |
| Skeletal Apprentice | 8 | | No | | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Silverback | 109 | | No | Blunt | 25% Blunt 10% Pierce |
| Skeletal Pup | 6 | | No | | -25% Blunt 5% Pierce 5% Cut 25% Arrow 5% Soul 100% Poison 100% Disease |
| Sheep | 2 | | No | Blunt | 50% Disease |
| Shark | 90 | | No | | |
| Skeletal Mage | 12 | | No | Blunt | -25% Blunt 25% Pierce 25% Cut 25% Arrow 25% Soul 100% Poison 100% Disease |
| Shadow Spider | 62 | | No | | 100% Poison |
| Shadow | 17 | | No | Cut | 50% Blunt 25% Pierce 25% Cut 25% Arrow 25% Nature 25% Soul 25% Mind 25% Body 25% Poison 25% Disease |
| Shade | 20 | | No | | 25% Pierce 25% Soul 25% Body 50% Disease |
| Sewer Rat | 23 | | No | Pierce | -4% Blunt 10% Cut |
| Swamp Slug | 27 | | No | | -10% Pierce 25% Disease |
| Skeletal Pet | 9 | | No | Blunt | -10% Blunt |
| Scorpion | 5 | | No | Pierce | -10% Blunt 25% Nature 25% Soul 25% Body 100% Poison |
| Schlag the Scorpiones | 20 | | Yes | | 100% Poison |
| Scary Spider | 105 | | No | | 25% Blunt 25% Cut -10% Nature 50% Mind 100% Poison |
| Savanna Lion | 125 | | No | Pierce | 20% Blunt 20% Soul -4% Mind |
| Sandy Claws | 135 | | Yes | Cut | 20% Blunt 25% Pierce 50% Cut 20% Soul 20% Mind |
| Skeletal Fiend | 78 | | No | | -5% Soul |
| Sand Sting | 65 | | Yes | | -10% Blunt 50% Arrow 15% Nature 100% Poison |